| SpongeBob's Boating Bash (USA) (NDSi Enhanced) | |
| SpongeBob's Surf & Skate - Roadtrip (Europe) (En,Fr,De,Es,Nl) | |
| SpongeBob's Surf & Skate - Roadtrip (Europe) (En,Fr,Es) | |
| SpongeBob's Truth or Square (USA) | |
| SpongeBobgwa Chingudeul (Korea) | |
| SpongeBobui Atlantis (Korea) | |
| Spooky Story (Germany) | |
| Spore - Kimi ga Tsukuru Hero (Japan) | |
| Spore Creatures (Europe) (En,Fr,De,Es,It,Nl) | |
| Spore Creatures (Japan) (En,Ja) | |
| Spore Creatures (Korea) | |
| Spore Creatures (USA) (En,Fr,De,Es,It,Nl) | |
| Spore Hero Arena (Europe) (En,Fr,De,Es,It,Nl) | |
| Spore Hero Arena (USA) (En,Fr,De,Es,It,Nl) | |
| Sports Collection (Europe) (En,Fr,De,It) | |
| Sports Island DS (Europe) (En,Fr,De,Es,It) | |
| Sprung - A Game Where Everyone Scores (USA) | |
| Sprung - The Dating Game (Europe) | |
| Spy | |
| ro - Shadow Legacy (Europe) (En,Fr,De,Es,It,Nl) | |
| Spyro - Shadow Legacy (USA) | |
| Squeeballs Party (Europe) (En,Fr,De,Es,It) | |
| Squeeballs Party (USA) | |
| Squishy Tank (USA) | |
| Star Fox Command (Europe) (En,Fr,De,Es,It) | |
| Star Fox Command (Japan) | |
| Star Fox Command (USA) | |
| Star Trek - Tactical Assault (Europe) | |
| Star Trek - Tactical Assault (USA) | |
| Star Wars - Battlefront - Elite Squadron (Europe) (En,Fr) | |
| Star Wars - Battlefront - Elite Squadron (Europe) (Es,It) | |
| Star Wars - Battlefront - Elite Squadron (Germany) | |
| Star Wars - Battlefront - Elite Squadron (USA) (En,Fr) | |
| Star Wars - Episode III - Revenge of the Sith (Europe) (En,Fr,De,Es,It,Nl) | |
| Star Wars - Episode III - Revenge of the Sith (USA) (En,Fr,De,Es,It,Nl) | |
| Star Wars - Episode III - Sith no Fukushuu (Japan) | |
| Star Wars - Lethal Alliance (Europe) (En,Fr,De,Es,It) | |
| Star Wars - Lethal Alliance (USA) (En,Fr,De,Es,It) | |
| Star Wars - The Clone Wars - Jedi Alliance (Europe) (En,Fr,De,Es) | |
| Star Wars - The Clone Wars - Jedi Alliance (USA) (En,Fr,De,Es) | |
| Star Wars - The Clone Wars - Republic Heroes (Europe) (En,Fr,De,Es,It) | |
| Star Wars - The Clone Wars - Republic Heroes (USA) (En,Fr,De,Es,It) | |
| Star Wars - The Force Unleashed (Europe) (En,Fr,De,Es,It) | |
| Star Wars - The Force Unleashed (Japan) | |
| Star Wars - The Force Unleashed (Korea) | |
| Star Wars - The Force Unleashed (USA) (En,Fr,De,Es,It) | |
| Star Wars - The Force Unleashed II (Europe) (En,Fr,De,Es,It) | |
| Star Wars - The Force Unleashed II (USA) (En,Fr,De,Es,It) | |
| Starz (Europe) (En,Fr,Es,It) | |
| Steal Princess - Touzoku Koujo (Japan) | |
| Steal Princess (USA) | |