| Zenses - Rainforest (Europe) (En,Fr,De,Es,It,Sv,No,Da) | |
| Zenses - Rainforest (USA) (En,Fr,Es) | |
| Zero kara Hajimeru - Otona no 5 Kakokugo Nyuumon - Ei, Futsu, Doku, I, Sei (Japan) | |
| Zero kara Kantan Chuugokugo DS (Japan) | |
| Zero kara Kantan Kankokugo DS (Japan) | |
| Zettai Karen Children DS - Dai-4 no Children (Japan) | |
| Zettai Onkan Otodamaster (Japan) | |
| Zettai Onkan Otodamaster (Japan) (Rev 1) | |
| Zettai Zetsumei Dangerous Jiisan DS - Dangerous Sensation (Japan) | |
| Zhu Zhu Pets (Europe) | |
| Zhu Zhu Pets (USA) | |
| Zhu Zhu Pets 2 - Featuring the Wild Bunch (USA) (En,Fr) (NDSi Enhanced) | |
| Zhu Zhu Pets featuring the Wild Bunch (Europe) (En,Fr,De,Es,It) (NDSi Enhanced) | |
| Zoey 101 - Field Trip Fiasco (USA) | |
| Zoids Battle Colosseum (Japan) | |
| Zoids Dash (Japan) | |
| Zoids Saga DS - Legend of Arcadia (Japan) | |
| Zombie Daisuki (Japan) | |
| Zombie Shiki - Eigo Ryoku Sosei Jutsu - English of the Dead (Japan) | |
| Zoo Hospital (Europe) | |
| Zoo Hospital (Europe) (En,Fr,De,Es,It) | |
| Zoo Hospital (USA) | |
| Zoo Keeper (Europe) (En,Fr,De,Es,It) | |
| Zoo Keeper (Japan) | |
| Zoo Keeper (USA) | |
| Zoo Quest - Puzzle Fun! (Europe) (En,Fr,De,Es,It,Nl,Sv,No,Da,Fi,Hu) | |
| Zoo Quest - Puzzle Fun! (USA) | |
| Zoo Tycoon 2 (Japan) | |
| Zoo Tycoon 2 (Korea) | |
| Zoo Tycoon 2 DS (Europe) (En,Fr,De,Es,It) | |
| Zoo Tycoon 2 DS (USA) | |
| Zoo Tycoon DS - Doubutsuen o Tsukurou! (Japan) | |
| Zoo Tycoon DS (Europe) | |
| Zoo Tycoon DS (Europe) (En,Fr) | |
| Zoo Tycoon DS (Europe) (Fr,De) | |
| Zoo Tycoon DS (USA) | |
| Zoo Vet - Endangered Animals (USA) | |
| Zorro - Quest for Justice (Europe) (En,Fr,De,Es,It) | |
| Zorro - Quest for Justice (USA) (En,Fr,De,Es,It) | |
| Zubo (Europe) (En,Fr,De,Es,It,Nl,Sv) | |
| Zubo (USA) (En,Fr,Es) | |
| Zuma's Revenge (USA) | |
| Zunou ni Asekaku Game Series! Vol. 1 - Cool 104 Joker & Setline (Japan) | |
| Zunou Nouryoku Koujou Machine - Touch de Zunoo DS (Japan) | |