| Eigo de Tabisuru - Little Charo (Japan) | |
| Eigo ga Nigate na Otona no DS Training - Eigo Zuke (Japan) | |
| Eigo ga Nigate na Otona no DS Training - Eigo Zuke (Japan) (Rev 1) | |
| Eigo ga Nigate na Otona no DS Training - Motto Eigo Zuke (Japan) | |
| Eigo o Taberu Fushigi na Ikimono - Marsh (Japan) | |
| Eigyoudou, The (Japan) | |
| Eijukugo Target 1000 DS (Japan) | |
| Eiken DS (Japan) | |
| Eiken DS Training (Japan) | |
| Eiken Kakomondai Shuuroku - Eiken DS 2 Deluxe (Japan) | |
| Eiken-ou - 2-kyuu Hen (Japan) | |
| Eiken-ou - 3-kyuu Hen (Japan) | |
| Eiken-ou - 4-kyuu Hen (Japan) | |
| Eiken-ou - Jun-2-kyuu Hen (Japan) | |
| Eikoh Seminar Koushiki DS Kyouzai - Chuugaku Eitango - Eitan Zamurai DS (Japan) | |
| Eikoh Seminar Koushiki DS Kyouzai - Koukou Eitango - Eitan Zamurai DS (Japan) | |
| Eikoh Seminar Koushiki DS Kyouzai - Shougakkou Eitango - Eitan Zamurai DS (Japan) | |
| Eindeloos Backgammon (Netherlands) | |
| Eindeloos Games To | |
| p 10 (Netherlands) | |
| Eindeloos Mahjong (Netherlands) (En,Nl) | |
| Eindeloos Mahjong 2 - Een Reis om de Wereld (Netherlands) | |
| Eindeloos Patience (Netherlands) | |
| Eitango Target 1900 DS (Japan) | |
| Eiyuu Senki - Laevatein (Japan) | |
| Elebits - Kai to Zero no Fushigi na Tabi (Japan) | |
| Elebits - Kaiwa Zeroui Sinbihan Yeohaeng (Korea) | |
| Elebits - The Adventures of Kai and Zero (USA) (En,Fr) | |
| Electroplankton (Europe) (En,Fr,De,Es,It) | |
| Electroplankton (Japan) | |
| Electroplankton (USA) | |
| Eledees - The Adventures of Kai and Zero (Europe) (En,Fr,De,Es,It) | |
| Element Girls - Love, Fashion & Friends (Europe) (En,Fr,De,Es,It) | |
| Element Girls - Style Your Life! (Europe) (Fr,De) | |
| Element Girls (Germany) | |
| Element Hunters (Japan) | |
| Element Hunters (Korea) | |
| Elemental Monster - Itsu Hashira Gami no Nazo (Japan) | |
| Elements of Destruction (Europe) (En,Fr,De,Es) | |
| Elements of Destruction (USA) | |
| Elf Bowling 1 & 2 (USA) | |
| Elite Beat Agents (Europe) | |
| Elite Beat Agents (France) | |
| Elite Beat Agents (Germany) | |
| Elite Beat Agents (Italy) | |
| Elite Beat Agents (Spain) | |
| Elite Beat Agents (USA) | |
| Elite Forces - Unit 77 (Europe) (En,Fr,De,Es,It) | |
| Elite Forces - Unit 77 (USA) (En,Fr,De,Es,It) | |
| Ellen Whitaker's Horse Life (Europe) (En,Fr,De,Es,It,Nl) | |
| Elminage - Yami no Miko to Kamigami no Yubiwa - DS Remix (Japan) | |