| Turn It Around (USA) | |
| Tus Amigos de Disney (Spain) | |
| TV Anime Fairy Tail - Gekitou! Madoushi Kessen (Japan) | |
| Twilight Syndrome - Kinjirareta Toshi Densetsu (Japan) | |
| U-Can - Penji Training DS (Japan) | |
| Uchi no 3 Shimai DS (Japan) | |
| Uchi no 3 Shimai DS 2 - 3 Shimai no Odekake Daisakusen (Japan) | |
| Uchida Yasuo DS Mystery - Meitantei Asami Mitsuhiko Series 'Fukutoshin Renzoku Satsujin Jiken' (Japan) | |
| Ukkari o Nakusou Bunshou Yomi Training - Yomitore (Japan) | |
| Ultimate Band (Europe) (En,Fr,De,Es,It,Nl) | |
| Ultimate Band (USA) (En,Fr,Es) | |
| Ultimate Game Room (USA) | |
| Ultimate Mortal Kombat (Europe) (En,Fr,De,Es,It) | |
| Ultimate Mortal Kombat (USA) (En,Fr,De,Es,It) | |
| Ultimate Puzzle Games - Sudoku Edition (USA) | |
| Ultimate Spider-Man (Europe) | |
| Ultimate Spider-Man (France) | |
| Ultimate Spider-Man (Germany) | |
| Ultimate Spider-Man (Italy) | |
| Ultimate Spider-Man (Japan) | |
| Ultimate Spider-Man (Spain) | |
| Ultimate Spider-Man (USA) | |
| Umezawa Yukari no Yasashii Igo (Japan) | |
| Umihara Kawase Shun - Second Edition Kanzen Ban (Japan) | |
| Umiuru to Sudoku Shiyo! - Nikoli Gensen 7 Dai Puzzle 555 Mon (Japan) | |
| Undercover - Dual Motives (Europe) (En,Fr,De,Es,It) | |
| Underground Pool (USA) | |
| Underwater Attack (USA) | |
| Underwater Puzzle - Echter Puzzlespass fuer Unterwegs (Europe) (En,Fr,De,Es,It) | |
| Unknown Soldier - Mokuba no Houkou (Japan) | |
| Uno 52 (Europe) (En,Fr,De,Es,It) | |
| Uno 52 (USA) | |
| Unoe Sangkwae Tongkwae - Teullin Geurim Jeonjip (Korea) | |
| Unou Ikusei - IQ Breeder - Pet to Nakayoku IQ Lesson (Japan) | |
| Unou Kaiten - Match Bou Puzzle DS (Japan) | |
| Unou no Tatsujin - GunBulleTrainer (Japan) | |
| Unou no Tatsujin - Hirameki Kosodate My Angel (Japan) | |
| Unou no Tatsujin - Soukai! Machigai Museum (Japan) | |
| Unou no Tatsujin - Soukai! Machigai Museum 2 (Japan) | |
| Unou Nouryoku Check Machine - Touch de Unoo! DS (Japan) | |
| Unou Tanren Unotan DS - Shichida Shiki Otona no Shun Kan Training (Japan) | |
| Unou Tanren Unotan DS - Shichida Shiki Otona no Sokudoku Training (Japan) | |
| Unsolved Crimes (Europe) (En,Fr,De,Es,It) | |
| Unsolved Crimes (USA) | |
| Up (Europe) | |
| Up (Europe) (Fr,De,Nl) | |
| Up (Europe) (Sv,No,Da) | |
| Up (Italy) | |
| Up (Korea) | |
| Up (Spain) | |